The Research Office

Wilson Hall
371 Wilson Boulevard
Rochester, Michigan 48309-4486
(location map)
(248) 370-2762
(248) 370-4111

Regulatory Compliance

At Oakland University, we adhere to laws, regulations, guidelines and specifications relevant to research processes. The Research Office will help you navigate through these processes. 

Export Control

The purpose of the federal export control regulations is to protect certain national and economic security interests.  The regulations may apply to some university activities even though, generally, there are exclusions for fundamental research and education.  While Oakland University is committed to academic freedom, the sharing of information and ideas, and public dissemination of knowledge, inclusive of citizens from non-U.S. nations, the university and its members must comply with the export control regulations or face penalties for any violations that occur.

Most of the relevant export control regulations are administered by one of three federal departments—State, Commerce, and Treasury.  Each of these departments has its own set of regulations, policies, and procedures, which are changeable and often conflict with each other.  Therefore, it is the goal of the Office of the Vice Provost for Research at Oakland University to provide relevant information, guidance, and education to investigators so that they can plan their activities to comply with these complex regulations.  In turn, investigators and other personnel must share the responsibility for recognizing the activities under their purview that may require review for compliance with export controls.

The resources on this website are a starting point, but more detailed discussions with Oakland University’s Office of Research Administration staff are welcome and often necessary for reaching an understanding and resolution about specific situations.  Click on any of the following resources:

  • Online CITI training.  To select the correct module:
    • Click on "Submit"
    • Click on "Add a course or update your learner group"
    • Scroll down to Question 6 and select CITI Export Controls
Financial Conflict of Interest (FCOI)

Compliance with Financial Conflict of Interest Regulations
New federal regulations on financial conflicts of interest (FCOI) in PHS-funded research took effect on August 24, 2012. The “Final Rule” replaces the 1995 regulations and applies to all researchers at Oakland University who are planning to apply for, or have received, grant funds from the Public Health Service (e.g., NIH) on or after August 24, 2012.   The Final Rule affects the definition, thresholds, disclosure and management of Financial Conflicts of Interest (FCOI).

The Final Rule makes it mandatory for investigators with PHS funding to complete required training.  This applies to the Principal Investigator or Program Director and all personnel who are responsible for the design, conduct or reporting of the PHS-funded work. “Investigator” includes sub-grantees, contractors, consortium participants, collaborators, and consultants. OU uses the on-line CITI module on FCOI to comply with this training requirement, but the Office of Research Administration can provide additional in-person training sessions upon request.

National Science Foundation (NSF)
OU's Research Policy and Operational Guidance for National Science Foundation Conflict of Interest (FCOI) is available.  This guidance applies to all researchers who are presently funded under an NSF grant or plan to submit an application for NSF funding. 

If you are a researcher with Significant Financial Interests related to your NSF-funded research, a fillable form version of the Disclosure Form is available. The form can be emailed to

If you have any questions, please contact Adeline Gonzales, Grant and Contract Officer, at or (248) 370-2753.

Human Pluripotent Stem Cell Research Oversight (HPSCRO) Committee

Human Pluripotent Stem Cell Research Oversight (HPSCRO) Committee

Derivation and/or use of human pluripotent stem cells (HPSCs) in research requires review and approval by the Oakland University (OU) HPSCRO Committee prior to initiation.  HPSCs include human embryonic stem cells and human induced pluripotent stem cells.  The HPSCRO committee will ensure that any HPSC research at OU is conducted according to the highest ethical standards and in accordance with all state and federal regulations and other applicable HPSC research guidelines.  The OU HPSCRO Committee guidelines and procedures for derivation and/or research use can be found in Oakland University Human Pluripotent Stem Cell Research Oversight (HPSCRO) Committee Guidelines.

Applications for initial review must be submitted to the Director of Regulatory Support at using the HPSCRO Application. Once approved, HPSC research will be registered with the HPSCRO Committee’s internal registry and will be valid for 3 years.  Applications for continuing review should be submitted using the continuing review application. Any modifications in approved research must be approved prior to initiation using the HPSCRO Modification form


1. The National Institutes of Health Guidelines for Human Stem Cell Research -

2. Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research -

For questions, contact the Director of Regulatory Support at or any of the HPSCRO Committee Members listed below.

HPSCRO Committee Members
Paul Megee, Ph.D., Chair
Judith Venuti, Ph.D., Alternate
Kevin Baker, Ph.D.
Rasul Chaudhry, Ph.D.
Kyeorda Kemp, Ph.D.
Gerard Madlambayan, Ph.D.
Gustavo Patino, M.D., Ph.D.
Luis Villa Diaz, DVM, MAppSc, Ph.D.

Nonvoting Members
Rebecca Sandborg, Ph.D.
Domenic Luongo, MSc, CHMM

Institutional Animal Care and Use Committee (IACUC)

The use of vertebrate animals in research, teaching, and testing requires the submission and approval of an IACUC application.  Applications for the use of vertebrate animals (AUVA), and request for revisions for any previously approved applications, are submitted through RAM 3.0.  Please note that use of the most current version of the application is mandatory and is located in RAM 3.0.

Review of Applications

The IACUC committee meets monthly to review applications. If you are preparing an application, please contact the committee chair for the deadline for applications to be reviewed at the next meeting. All applications are due at least 10 days prior to the next meeting.

The February IACUC meeting is scheduled for Tuesday, February 18, at 9:00 a.m.

The March IACUC meeting is scheduled for Tuesday, March 24, at 9:00 a.m.

The April IACUC meeting is scheduled for Tuesday, April 21, at 9:00 a.m.

The committee reviews the scientific merit of the proposed research as it bears on the humane or proper use of animals. The committee performs program reviews and an inspection of facilities at least once every six months.

The Top 10 Reasons Why Protocol Applications Are Deferred

Pre-Review Checklist - IACUC Protocol

The program for animal care and use is supported by the Biomedical Research Support Facility

Training Requirements

The Oakland University Institutional Animal Care and Use Committee (IACUC) requires that all Principal Investigators with an approved IACUC Application for the Use of Vertebrate Animals (AUVA), and any  personnel listed on those applications, complete Collaborative Institutional Training Initiative (CITI) Courses before they are allowed to begin working  on the project This requirement is satisfied by the completion of CITI Training. 

Oakland University Guidelines and Policies


Institutional Biosafety Committee (IBC)

All research, teaching, and studies at Oakland University that involve recombinant DNA, infectious agents, and/or cultured cell lines must be approved by the  Institutional Biosafety Committee (IBC)  prior to any work performed in the laboratory.

  • Human/Primate derived materials
  • Bloodborne Pathogens
  • Recombinant DNA
  • Infection agents including:
    • Bacteria
    • Virus
    • Fungi
    • Prion
  • Biologically-derived toxins
  • Cultured cell lines

Project Application and Revision Via RAM 3.0

  • IBC scheduled to meet monthly
  • Applications must be submitted 2 weeks prior to scheduled meetings. 
  • Access to the Research Application Manager:    RAM 3.0.
Radiation Safety (RSC)

Radioactive material (including machinery producing ionizing radiation) can only be used by authorized Oakland University permit holders or under the supervision of a permit holder. User permits are issued by the Oakland University Radiation Safety Committee (RSC). User permits are issued to the full-time OU faculty members or principal investigators only. All others must work under the supervision of a full-time faculty member.

Full-time faculty members can apply to the RSC for a user permit by submitting a Radiation User Permit Application.  Please contact Radiation Safety Officer, Domenico Luongo, to get the electronic copy.  The committee will issue a user permit only after reviewing the application. Three-year user permits are issued after an initial probationary one-year user permit. Permit holders are responsible for the proper use of all radioisotopes or radiation producing machinery, proper maintenance of the facilities used for research, and proper maintenance of all required records. The specific, detailed instructions on procedures and requirements for the use of radioactive materials at Oakland is referenced in the Oakland University Safety and Procedures Manual for the Use of Radioisotopes in Laboratories (pdf).

Permit holders are responsible for meeting Oakland University training requirements and standards. Every individual working with, or in the vicinity of radioactive materials, must receive instruction and training commensurate with their duties before beginning any work. In addition, all individuals must be retrained once every three years and/whenever there is a significant change in duties, regulations, or terms of the university’s license of the investigators user permit. A description of these requirements can be found in the Oakland University Safety and Procedures Manual for the Use of Radioisotopes in Laboratories (pdf).

Permit holders should know that federal and state agencies routinely conduct inspections – some unannounced – including inspections of records maintained by permit holders. In addition, periodic audits of laboratories, and inspections of isotope records, are conducted by the Radiation Safety Officer (RSO) or a member of the RSO’s staff. All inspections, including inspections of records, will be done as to minimize the disruption of normal laboratory functions. They will be unannounced.

For questions regarding radiation safety and/or radiation permits contact Domenico Luongo, RSO, at (248) 370-4314, email or visit Laboratory Safety and Compliance.

Responsible Conduct of Research Training

Researchers must note that several federal funding agencies require training in the Responsible Conduct of Research (RCR).   The specific training requirements are agency-dependent.

National Science Foundation
The National Science Foundation (NSF) requires that all student researchers funded by NSF receive training in the RCR. This requirement applies to undergraduates, graduate students, and postdoctoral researchers who are supported by NSF to conduct research. View the relevant regulations.

In order to satisfy this training requirement, which took effect in January 2010, we remind you to have your student researchers take the required training when they begin their NSF-funded research.   For this purpose, Oakland University provides on-line RCR training from the Collaborative Institutional Training Initiative (CITI).   Instructions for signing on to the required RCR modules are as follows:

  • After accessing CITI training, either register as a new user or log in as usual, then click on “Submit”
  • Click on “Add a course or update your learner groups.”
  • Scroll down to Question 4 and select “RCR for NSF & NIH Researchers.”

National Institutes of Health
Similar training is required for personnel funded on NIH grants that have a training component.   For these grants, face-to-face educational sessions are required in addition to the on-line RCR modules from CITI.   These NIH requirements were updated in November 2009.

U.S. Department of Agriculture
Recipients of USDA funding requires program directors, faculty, undergraduate students, graduate students, postdoctoral researchers, and any staff participating in the research to undergo training and oversight in the RCR. Completion of the CITI Program training for RCR will satisfy the training requirement. The USDA requirements in the RCR training became effective February 2013.

Please contact our office if you have questions.