Department of Chemistry

Mathematics and Science Center,
Room 260
146 Library Drive
Rochester, MI 48309-4479
(location map)
(248) 370-2320
fax: 370-2321

Powerful confocal microscope advances neurodegeneration research

A new Leica spinning-disk confocal microscope was installed in the Department of Chemistry. This powerful fluorescence microscope, managed by Assistant Professor, Dr. Adam Avery, is equipped with state-of-the-art objectives, five laser channels and a sensitive CMOS camera. The instrument will advance Dr. Avery's research into neurodegenerative mechanisms, and will be an asset to Oakland's research community.

Screening for a treatment for spinocerebellar ataxia

Dr. Adam Avery's research into the molecular mechanisms underlying the neurological disorder, spinocerebellar ataxia type 5, has entered an exciting translational phase. In a NIH funded consortium with investigators at the University of Minnesota, the Avery lab is working to optimize a biosensor that senses the aberrant molecular interactions of the mutant protein, β-spectrin. Following optimization, large scale screening of small molecule libraries will be performed to identify candidate drugs that reduce the aberrant binding of mutant spectrin to its target proteins.

Breakthrough publication in Nature Communications

An international collaboration including Oakland researchers, Distinguished Prof. Michael Sevilla and Research Professors Anil Kumar and Amitava Adhikary, along with scientists from France, Japan and China, has resulted in an article in Nature Communications. The work presents a break in the understanding of the role of the electron in radiation damage to DNA.

NSF awards grant to interdisciplinary team to develop new sensor technology

Oakland University professors Xiangqun Zeng and Ziming Yang have teamed up with others to develop various sensors that can operate under harsh Arctic conditions.  View NSF awards for details.      

Department of Chemistry

The Department of Chemistry offers a full curriculum in undergraduate and graduate education in the chemical sciences. 

Our faculty are committed to providing the highest quality teaching and research. Research participation by undergraduates is a distinctive part of the department's activity. Our students have the opportunity to carry out research projects at the forefront of chemical, biochemical, and environmental research. Undergraduates often publish their research in internationally recognized journals as well as present their work at national meetings of the Student Affiliates of the American Chemical Society

The department is housed in the Mathematics and Science Center (MSC) with advanced research laboratory facilities and renovated teaching laboratories. We are well-equipped with modern instrumentation for chemical research and teaching. Major instruments include high-performance computational chemistry facilities, advanced instrumentation such as Nuclear Magnetic Resonance (NMR), Electron Spin Resonance (ESR), Inductively Coupled Plasma (ICP)- and Gas Chromatography (GC)-mass spectrometers; Infrared (IR), UV-visible and fluorescence spectrometers; dry boxes, a solvent purification system; and instruments for biochemistry such as flow cytometers, ultracentrifuges, and cell culture facilities. Recently, we installed a new Liquid Chromatography Time of Flight (TOF LC)-mass spectrometer.

Alzheimer’s disease is a progressive brain disorder, which affects mainly memory and thinking skills and that currently has no cure.

I started working on Alzheimer’s disease after taking Dr. Martic’s class last year and since I have a background in pharmacy, thought it would be incredible to give my contribution to research and finding a cure for disease.

I’m Albanian. And I left my home country after high school. When I was nineteen I moved to Italy to Rome to study pharmacy. After finishing pharmacy, I worked as a pharmacist for six years and I lived there for about twelve years before moving to the United States about two years ago. I first moved to study English for a whole year but after one semester I got accepted into a chemistry program, master’s program.

So here we have different samples of the protein of interest that will be loaded on the gel and then we will apply an electrical field to separate the protein based on their molecular weight.

I hope to find, in this sample, a reduced phosphorylation in the presences of the antibody compared to the sample where the protein isn’t phosphorylated in the absence of the antibody.

It will help us to better understand tau protein by chemistry the effects of antibodies on tau protein phosphorylation and maybe find a cure for Alzheimer’s disease.