Dr. Banes-Berceli's research interests are in physiological and molecular aspects of cardiovascular diseases and intracellular signaling. She is currently investigating hypertension and the renal and vascular complications of diabetes. Her research projects involve using a combination of an in vivo physiological approach as well as a molecular approach. The following research projects are currently in progress:

1. ANG II and JAK2 interactions in hypertension
2. Regulation of protein phosphatases which control the JAK/STAT in vivo
3. Mechanisms of serotonin's interaction with angiotensin II and ET-1

Banes AK, Shaw S, Tawfik A, Patel B, Ogbi S, Fulton D and Marrero MB. Activation of the JAK/STAT Pathway in Vascular Smooth Muscle by Serotonin is Independent of Reactive Oxygen Species. Am J Physiol Cell Physiol.288: 805-812, 2005.

Banes-Berceli AK, Ogbi S, Tawfik A, Patel B, , Shirley A, Pollock DM, Fulton D, Marrero MB. Activation of the JAK/STAT Pathway by Endothelin-1 in Vascular Smooth Muscle: In Vivo and In Vitro Evidence of the Involvement of NAD(P)H -derived Reactive Oxygen Species. J Vasc Pharmacol 43: 310-319, 2005.

Tawfik, A., Jin, L., Banes-Berceli, A.K. , Caldwell, R.B., Ogbi, S., Shirley, A., Barber, D., Catravas, J.D., Stern, D.M., Fulton, D., Caldwell, R.W., and Marrero, M.B. Hyperglycemia-Induced Reactive Oxygen Species Mediates Apoptosis in Aortic Endothelial Cells through Janus Kinase 2. J Vasc Pharmacol 43:320-326, 2005.

Marrero MB, Banes-Berceli AK, Stern DM, Eaton DC. Role of JAK/STAT signaling pathway in diabetic nephropathy. Am J Physiol Renal Physiol 290:F762- F768, 2006.

Banes-Berceli, A.K., Shaw, S., Ma, G., Ogbi, S., Shirley, A., Caldwell, R.W., Stern, D.M., Fulton, D., Marrero, M.B. Effect of Simvastatin on High Glucose-and Angiotensin II-Induced Activation of the JAK/STAT Pathway in Mesangial Cells. Am J Physiol Renal Physiol. 291: F116-121, 2006.

Banes-Berceli, A, Ketsawatsomkron P, Ogbi S, Patel B, Pollock DM, Marrero MB. Angiotensin II (ANG II) and Endothelin-1 (ET-1) augment the vascular complications of diabetes via JAK2. Am J Physiol Heart and Circ Physiol. 293: 1291-1299, 2007