Dr. Takayama is internationally renowned for development of microfluidic devices and applying their use in cell culture and handling including stem cell culture and handling. He is currently a Professor in the Department of Biomedical Engineering and the Macromolecular Science and Engineering Program at the University of Michigan. He is also WCU Visiting Professor at the Ulsan National Institute of Science and Technology (UNIST) in South Korea.
His research interests (B.S. and M.S. from the University of Tokyo in 1994, his Ph.D. degree in chemistry from the Scripps Research Institute in 1998) started with organic synthesis of molecules that mediate biological chemical communication. Subsequently he became interested in evaluating the function of synthesized molecules in engineered bio-microsystems and pursued postdoctoral studies at Harvard University as a Leukemia and Lymphoma Society Fellow. His current research interests are Micro/nanofluidics, Cellular microenvironment engineering including stem cell cultures, and Epigenetics. He constructs microfluidic models of the body such as artificial oviducts for enhanced in vitro fertilization treatment, microtissue engineered models of lung injury, and models of cancer metastasis for drug testing. He also develops aqueous two phase system micropatterning technologies, self-switching fluidic circuits, and nanofluidic single molecule DNA and chromatin analysis systems.
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